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2021

  • 2 min read

Zn(II) binding causes interdomain changes in the structure and flexibility of the human prion protein published in Nature Scientific Reports

Our research paper titled Zn(II) binding causes interdomain changes in the structure and flexibility of the human prion protein, authored by Maciej Gielnik, Michał Taube, Lilia Zhukova, Igor Zhukov, Sebastian K. T. S. Wärmländer, Željko M. Svedružić, Wojciech M. Kwiatek, Astrid Gräslund, and Maciej Kozak, has been published in Volume 11 of Nature journal Scientific Reports.

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Co-Aggregation of S100A9 with DOPA and Cyclen-Based Compounds Manifested in Amyloid Fibril Thickening without Altering Rates of Self-Assembly published in MDPI International Journal of Molecular Sciences

Our research paper titled Co-Aggregation of S100A9 with DOPA and Cyclen-Based Compounds Manifested in Amyloid Fibril Thickening without Altering Rates of Self-Assembly, authored by Lili Arabuli, Igor A. Iashchishyn, Nina V. Romanova, Greta Musteikyte, Vytautas Smirnovas, Himanshu Chaudhary, Željko M. Svedružić, and Ludmilla A. Morozova-Roche has been published in Volume 22 Issue 16 of MDPI International Journal of Molecular Sciences.

  • 2 min read

Polyoxometalates as Effective Nano-inhibitors of Amyloid Aggregation of Pro-inflammatory S100A9 Protein Involved in Neurodegenerative Diseases published in ACS Applied Materials & Interfaces

Our research paper titled Polyoxometalates as Effective Nano-inhibitors of Amyloid Aggregation of Pro-inflammatory S100A9 Protein Involved in Neurodegenerative Diseases, authored by Himanshu Chaudhary, Igor A. Iashchishyn, Nina V. Romanova, Mark A. Rambaran, Greta Musteikyte, Vytautas Smirnovas, Michael Holmboe, C. André Ohlin, Željko M. Svedružić, and Ludmilla A. Morozova-Roche (research group), has been published in Volume 13, Issue 23 of ACS journal Applied Materials & Interfaces.

  • 2 min read

Natural Compound from Olive Oil Inhibits S100A9 Amyloid Formation and Cytotoxicity: Implications for Preventing Alzheimer's Disease published in ACS Chemical Neuroscience

Our research paper titled Natural Compound from Olive Oil Inhibits S100A9 Amyloid Formation and Cytotoxicity: Implications for Preventing Alzheimer's Disease, authored by Manuela Leri, Himanshu Chaudhary, Igor A. Iashchishyn, Jonathan Pansieri, Željko M. Svedružić, Silvia Gómez Alcalde, Greta Musteikyte, Vytautas Smirnovas, Massimo Stefani, Monica Bucciantini, and Ludmilla A. Morozova-Roche (research group), has been published in Volume 12, Issue 11 of ACS journal Chemical Neuroscience.

  • 2 min read

Structural Analysis of the Simultaneous Activation and Inhibition of γ-Secretase Activity in the Development of Drugs for Alzheimer's Disease published in MDPI Pharmaceutics

Our research paper titled Structural Analysis of the Simultaneous Activation and Inhibition of γ-Secretase Activity in the Development of Drugs for Alzheimer's Disease, authored by Željko Svedružić, Katarina Vrbnjak, Manuel Martinović, and Vedran Miletić, has been published in special issue Covalent Inhibitors as Selective Drug Candidates of MDPI open access journal Pharmaceutics.