News
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Zn(II) binding causes interdomain changes in the structure and flexibility of the human prion protein
Our research paper titled Zn(II) binding causes interdomain changes in the structure and flexibility of the human prion protein, authored by Maciej Gielnik, Michał Taube, Lilia Zhukova, Igor Zhukov, Sebastian K. T. S. Wärmländer, Željko M. Svedružić, Wojciech M. Kwiatek, Astrid Gräslund, and Maciej Kozak, has been published in Volume 11 of Nature journal Scientific Reports.
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Polyoxometalates as Effective Nano-inhibitors of Amyloid Aggregation of Pro-inflammatory S100A9 Protein Involved in Neurodegenerative Diseases
Our research paper titled Polyoxometalates as Effective Nano-inhibitors of Amyloid Aggregation of Pro-inflammatory S100A9 Protein Involved in Neurodegenerative Diseases, authored by Himanshu Chaudhary, Igor A. Iashchishyn, Nina V. Romanova, Mark A. Rambaran, Greta Musteikyte, Vytautas Smirnovas, Michael Holmboe, C. André Ohlin, Željko M. Svedružić, and Ludmilla A. Morozova-Roche (research group), has been published in Volume 13, Issue 23 of ACS journal Applied Materials & Interfaces.
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Natural Compound from Olive Oil Inhibits S100A9 Amyloid Formation and Cytotoxicity: Implications for Preventing Alzheimer's Disease
Our research paper titled Natural Compound from Olive Oil Inhibits S100A9 Amyloid Formation and Cytotoxicity: Implications for Preventing Alzheimer’s Disease, authored by Manuela Leri, Himanshu Chaudhary, Igor A. Iashchishyn, Jonathan Pansieri, Željko M. Svedružić, Silvia Gómez Alcalde, Greta Musteikyte, Vytautas Smirnovas, Massimo Stefani, Monica Bucciantini, and Ludmilla A. Morozova-Roche (research group), has been published in Volume 12, Issue 11 of ACS journal Chemical Neuroscience.
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Structural Analysis of the Simultaneous Activation and Inhibition of γ-Secretase Activity in the Development of Drugs for Alzheimer's Disease
Our research paper titled Structural Analysis of the Simultaneous Activation and Inhibition of γ-Secretase Activity in the Development of Drugs for Alzheimer’s Disease, authored by Željko Svedružić, Katarina Vrbnjak, Manuel Martinović, and Vedran Miletić, has been published in special issue Covalent Inhibitors as Selective Drug Candidates of MDPI open access journal Pharmaceutics.
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Diverse SARS-CoV-2 variants preceded the initial COVID-19 outbreak in Croatia
Our brief report titled Diverse SARS-CoV-2 variants preceded the initial COVID-19 outbreak in Croatia, authored by Filip Rokić, Lovro Trgovec-Greif, Neven Sučić, Noa Čemeljić, Đurđica Cekinović Grbeša, Željko Svedružić, Tomislav Rukavina, Oliver Vugrek, and Igor Jurak, has been published in Archives of Virology.
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Structural Analysis of Simultaneous Activation and Inhibition of Gamma-Secretase Activity in Development of Drugs for Alzheimer's Disease
Our research preprint titled Structural Analysis of Simultaneous Activation and Inhibition of Gamma-Secretase Activity in Development of Drugs for Alzheimer’s Disease, authored by Željko Svedružić, Katarina Vrbnjak, Manuel Martinović, and Vedran Miletić, has been uploaded to BioRxiv.
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Substrate Channeling via a Transient Protein-Protein Complex: The case of D-Glyceraldehyde-3-Phosphate Dehydrogenase and L-Lactate Dehydrogenase published in Nature Scientific Reports
Our research paper titled Substrate Channeling via a Transient Protein-Protein Complex: The case of D-Glyceraldehyde-3-Phosphate Dehydrogenase and L-Lactate Dehydrogenase, authored by Željko Svedružić, Ivica Odorčić, Christopher Chang, and Draženka Svedružić, has been published today in Nature Scientific Reports.
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BioSFGroup featured in Novi list's VOX academiae
BioSFGroup’s Patrik Nikolić and Dr. Vedran Miletić’s figure was featured in Novi list’s University of Rijeka-themed monthly attachment VOX academiae issue 27 (page 2 and page 3: Epicentar znanstvenika u borbi protiv klimatskih promjena i virusa).
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Substrate Channeling via a Transient Protein-Protein Complex: The case of D-Glyceraldehyde-3-Phosphate Dehydrogenase and L-Lactate Dehydrogenase published on bioRxiv
Our research preprint titled Substrate Channeling via a Transient Protein-Protein Complex: The case of D-Glyceraldehyde-3-Phosphate Dehydrogenase and L-Lactate Dehydrogenase, authored by Željko Svedružić, Ivica Odorčić, Christopher Chang, and Draženka Svedružić, has been uploaded to BioRxiv.
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European Researchers' Night 2019
European Researchers’ Night 2019 in Rijeka took place in Tower Center on Friday, 27th September 2019. BioSFGroup participated with the topic Supercomputer Bura: our window to the world of molecules.
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BioSFGroup featured in Novi list's VOX academiae
BioSFGroup’s Prof. Dr. Željko Svedružić and Dr. Vedran Miletić were featured in Novi list’s University of Rijeka-themed monthly attachment VOX academiae issue 19 (page 1; pages 6–7: Istraživači Odjela za biotehnologiju približavaju znanosti građanima).
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Pro-Inflammatory S100A9 Protein Aggregation Promoted by NCAM1 Peptide Constructs published in ACS Chemical Biology
Our research paper titled Pro-Inflammatory S100A9 Protein Aggregation Promoted by NCAM1 Peptide Constructs, authored by Jonathan Pansieri, Lucija Ostojić, Igor A. Iashchishyn, Mazin Magzoub, Cecilia Wallin, Sebastian K. T. S. Wärmländer, Astrid Gräslund, Mai Nguyen Ngoc, Vytautas Smirnovas, Željko Svedružić, and Ludmilla A. Morozova-Roche (research group), has been published today in ACS Chemical Biology.
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European Researchers' Night 2018
European Researchers’ Night 2018 in Rijeka took place in Tower Center on Friday, 28th September 2018. BioSFGroup participated with the topic Microscope vs. supercomputers in pharmacy (supercomputers are 21st century microscopes).
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In silico design of the first DNA-independent mechanism-based inhibitor of mammalian DNA methyltransferase Dnmt1 published in PLOS ONE
Our research paper titled In silico design of the first DNA-independent mechanism-based inhibitor of mammalian DNA methyltransferase Dnmt1, authored by Vedran Miletić, Ivica Odorčić, Patrik Nikolić, and Željko Svedružić, has been published today in PLOS ONE, the flagship Open Access journal.
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BioSFGroup featured in student journal Biotech – znanost u društvu
BioSFGroup’s Prof. Dr. Željko Svedružić, Patrik Nikolić, and Vedran Miletić were featured in in University of Rijeka Department of Biotechnology student journal Biotech – znanost u društvu issue 3 (also available on Issuu) from December 2014 (front page; pages 9–16: interview: doc. dr. sc. Željko Svedružić; page 17: interview: Patrik Nikolić; pages 18–19: interview: Vedran Miletić).